One of the most common symptoms of acid reflux is heartburn or a burning in the chest. Antacids- such as mylanta or maalox may improve symptoms, but a medicine that lowers the acidity in the stomach is more powerful. H2 blockers-Zantac and pepcid lower the acidity. The proton pump inhibitors- prilosec, protonix and nexium block acid production. Long term acid reflux can lead to Barrett's esophagus, which is a precancerous condition.