Home > Heart Disease > Anatomy of the Heart and Plaque or Blockage Get the Flash Player to see this player. Rate: (Click the stars to rate) Published on Apr 12, 2015 by Cardiosmart, Views: 7151 Anatomy of the Heart and Plaque or Blockage. Plaque can build up in the arteries that supply the heart with blood, and cause symptoms, such as chest pain. Sometimes the plaque ruptures and causes a heart attack.