Home > Gastroenterology > Antidepressants for IBS Get the Flash Player to see this player. Rate: (Click the stars to rate) Published on Aug 03, 2008 by PWhorwell, Views: 7225 Dr Peter Whorwell, Professor of Gastroenterology at the Univ. of Manchester, discussses the use of antidepressants for IBS. Symptoms of Irritable bowel syndrome can be improved with antidepressant therapy.