Symptoms of carpal tunnel syndrome: The most common symptom of carpal tunnel is pain in the hands, it is frequently at night or early in the morning. The other common symptoms of carpal tunnel syndrome include parasthesias, which is the feeling of pins and needles, or tingling of the hands, and loss of dexterity, and weakness of the hands. Dr. Charles Melone, Director of Hand Surgery, Beth Israel Med. Ctr. Symptoms of Carpal Tunnel Syndrome.