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Liver Disease causes dysfunction of the liver which produces some of the factors which help your blood clot. For this reason there can be bleeding associated with liver disease. People with liver failure or cirrhosis will commonly bleed after surgery or into the GI tract. Unexplained bruising or easy bruising is a common finding. A blood test, the PT/INR, is used to measure the risk of bleeding. Plasma transfusions are commonly used, and a few will need liver transplantation.
Multiple Myeloma
Chronic Lymphocytic Leukemia: Dr. Tim Call, a hematologist/oncologist at the Mayo Clinic, discuss CLL- Chronic Lymphocytic Leukemia. The average age of diagnsosis is in the 60's. It is frequently found on blood test , with a high white blood count. A confirmatory test using flow cytometry is usually performed. Staging includes physical exam, blood tests- LDH and beta 2 microglobulin.
CML-Chronic Myeloid Leukemia: CML can be a fatal disease if it goes untreated, however recent breakthroughs in treatment have been very successful. CML is caused by a genetic change that occurs in your body with a switch in chromosome 9 and 22, this is called the Philadelphia Chromosome. This causes a buildup of a certain protein. Imatinib (gleevec) is a medication to prevent buildup of this protein.
Coumadin (warfarin) is a potent blood thinner that is used to treat different conditions that require blood thinning, such as DVT(blood clot in the leg), pulmonary embolus, atrial fibrillation, and mechanical heart valves. The major complication of coumadin is bleeding. When you are on coumadin, you will need to check a blood test- the PT/INR. Sandra Takami, PharmD, a doctor of pharmacology.
Essential Thrombocythemia- ET, means too many platelets in your blood. Platelets are the type of cell involved in clotting. ET is a myeloproliferative disease, which is a group of diseases when the bone marrow make too many cells. Symptoms can be clotting, bleeding, nose bleeds, easy bruising, fatigue, bone pain, or a rash. It is diagnosed from a blood test. A bone marrow biopsy may be needed. Treatment includes aspirin, hydroxyurea, and interferon.
Hereditary Spherocytosis is a cause on anemia, this animated video shows you why. In this disease, because of a genetic defect, the red blood cells become abnormal in shape-like a sphere. This causes them to be destroyed in the spleen, causing anemia and an enlarged spleen.
Dr Anas Younes, an oncologist from MD Anderson in Houston, Texas, discusses the Hodgkins Lymphoma. Standard chemotherapy treatment is a regimen called ABVD. Some will require stem cell transplantation or newer treatment called targeted therapy, including monoclonal antibodies. An early sign of lymphoma includes easy bruising.
Indications of Iron Deficiency.
Free Hematology Videos and Doctor Videos on Hematology From VideoMD.com
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