Ask VideoMD.com: Takotsubo Cardiomyopathy or Broken Heart Syndrome. One of the charectors on the HBO hit show Entourage developed this problem in the show, and our viewer asked if it was real. It is a real medical problem that happens to people under severe stress, such as the death of a loved one. The symptoms and initial findings mimic a heart attack, but doctors find no blockages in the heart arteries. It is a serious problem that requires treatment, but has a good prognosis.