Home > Hematology > What is Multiple Myeloma? Get the Flash Player to see this player. Rate: (Click the stars to rate) Published on Apr 06, 2011 by NebraskaMedCenter, Views: 4674 The Nebraska Medical Center's multiple myeloma specialists Edward Faber, MD and Julie Vose, MD, discuss the cancerous bone disease which affects certain white blood cells called plasma cells. Symptoms include holes in the bone and can lead to severe pain, fractures and weakness. Often these symptoms resemble other bone diseases. Test such as x-ray, magnetic resonance imaging (MRI) and bone marrow biopsy can be used to diagnose multiple myeloma.