Home > Lung Disease > Asthma Prevention Get the Flash Player to see this player. Rate: (Click the stars to rate) Published on Oct 08, 2008 by JamesLi, Views: 4885 Asthma commonly runs in families, so genetics clearly plays a role. It is not clear that Asthma can be prevented, but certainly in people with asthma, exacerbations can be avoided with certain preventive measures. Most importantly, people with asthma, or at risk for asthma need to avoid all smoke exposure, including second hand smoke. Dr James Li, the Chair of Allergic Diseases at the Mayo Clinic, discusses asthma prevention.