Home > Hematology > Essential Thrombocythemia Get the Flash Player to see this player. Rate: (Click the stars to rate) Published on Dec 08, 2009 by RubenMesa, Views: 6159 Essential Thrombocythemia- ET, means too many platelets in your blood. Platelets are the type of cell involved in clotting. ET is a myeloproliferative disease, which is a group of diseases when the bone marrow make too many cells. Symptoms can be clotting, bleeding, nose bleeds, easy bruising, fatigue, bone pain, or a rash. It is diagnosed from a blood test. A bone marrow biopsy may be needed. Treatment includes aspirin, hydroxyurea, and interferon.