Home > Pediatrics > Myomyectomy For Hypertrophic Cardiomyopathy Get the Flash Player to see this player. Rate: (Click the stars to rate) Published on Aug 22, 2009 by HSchaff, Views: 5476 Hypertrophic cardiomyopathy is a genetic disease which causes the heart muscle to be abnormally thick. Patients that can not be treated adequately with medical therapy sometimes have to undergo surgery. This surgery is called a myomyectomy, most commonly done on the septum (or middle) of the heart.